P&L LÀ GÌ

Biological Activity for Substance P

Substance Phường is a sensory neuropeptide và inflammatory mediator. Exerts excitatory effects on central và peripheral neurons, constricts bronchioles và is involved in pain transmission.

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Technical Data for Substance P

M. Wt 1347.6
Formula C63H98N18O13S
Sequence RPKPQQFFGLM

(Modifications: Met-11 = C-terminal amide)

Storage Store at -20°C
Purity ≥95% (HPLC)
CAS Number 33507-63-0
PubChem ID 36511
InChI Key ADNPLDHMAVUMIW-CUZNLEPHSA-N
Smiles NH>(CCSC)C(N)=O

The technical data provided above is for guidance only. For batch specific data refer lớn the Certificate of Analysis.

realchampionshipwrestling.com products are intended for laboratory research use only, unless stated otherwise.

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References for Substance P

References are publications that support the biological activity of the sản phẩm.

Andoh et al (1998) Substance P. induction of itch-associated response mediated by cutaneous NK1 tachykinin receptors in mice. J.Pharmacol.Exp.Ther. 286 1140 PMID:9732370 Pernow et al (1983) Substance P.. Pharmacol.Rev. 35 85 PMID:6196797 Walsh et al (1995) Substance P-induced inflammatory responses in guinea-pig skin: the effect of specific NK1 receptor antagonists và the role of endogenous mediators. Br.J.Pharmacol. 114 1343 PMID:7541689 Merchồng Index 12 9032 If you know of a relevant reference for Substance Phường, please let us know.


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Keywords: Substance P, Substance Phường supplier, Sensory, neuropeptide, inflammatory, mediators, Tachykinin, Non-Selective sầu, Neurokinin, Receptors, agonists, SubstancePhường, neuropeptides, Other, 1156, realchampionshipwrestling.com Bioscience


15 Citations for Substance P

Citations are publications that use realchampionshipwrestling.com products. Selected citations for Substance Phường include:

Howe et al (2004) Role of neurokinin 3 receptors in supraoptic vasopressin & oxyt. neurons. J Biomol Screen 24 10103 PMID:15537880

Alsaqati et al (2013) Investigation of the functional expression of purine & pyrimidine receptors in porcine isolated pancreatic arteries. Purinergic Signal 10 241 PMID:24310605

Hur & Park (2013) Long-term potentiation of excitatory synaptic strength in spinothalamic tract neurons of the rat spinal cord. Korean J Physiol Pharmacol 17 553 PMID:24381506

Hanson et al (2009) A homogeneous fluorescent live-cell assay for measuring 7-transmembrane receptor activity and agonist functional selectivity through β-arrestin recruitment. Antioxid Redox Signal 14 798 PMID:19531663


Li et al (2009) Activation of glycoren synthase kinase-3 β is required for hyperDA và D2 receptor-mediated inhibition of synaptic NMDA receptor function in the rat prefrontal cortex. J Neurosci 29 15551 PMID:20007479

Gutierrez and Boadomain authority (2019) Neuropeptide-induced modulation of carcinogenesis in a metastatic breast cancer cell line (MDA-MB-231LUC+). Cancer Cell Int 18 216 PMID:30598641

Nogueras-Ortiz (2017) Retromer stops beta-arrestin 1 mediated signaling from internalized cannabinoid 2 receptors. Mol Biol Cell 28 3554 PMID:28954865

Wan et al (2017) Endomorphin-2 Inhibition of Substance P Signaling within Lamina I of the Spinal Cord Is Impaired in Diabetic Neuropathic Pain Rats. Front Mol Neurosci 9 167 PMID:28119567

Fisher et al (2015) Increased CCN2, substance P và tissue fibrosis are associated with sensorimotor declines in a rat Model of repetitive overuse injury. J Cell Commun Signal 9 37 PMID:25617052

Robery et al (2011) Investigating the effect of emetic compounds on chemotaxis in Dictyostelium identifies a non-sentient model for bitter and hot tastant research. PLoS One 6 e24439 PMID:21931717

Shanley et al (2011) Evidence for regulatory diversity và auto-regulation at the TAC1 locus in sensory neurones. J Neurosci 8 10 PMID:21294877

Kowtharapu et al (2018) Role of Corneal Stromal Cells on Epithelial Cell Function during Wound Healing. Int J Mol Sci 19 PMID:29401709

Frara et al (2018) Substance Phường increases CCN2 dependent on TGF-beta yet Collaren Type I via TGF-beta1 dependent và independent pathways in tenocytes. Connect Tissue Res 59 30 PMID:28399671

Chen et al (2014) μ-Opioid receptor inhibition of substance P release from primary afferents disappears in neuropathic pain but not inflammatory pain. Neuroscience 267 67 PMID:24583035

Wease và Davies (2005) Substance P. selectively decreases paired pulse depression in the rat hippocampal slice. BMC Neurosci 6 66 PMID:16305744


Do you know of a great paper that uses Substance P from realchampionshipwrestling.com? Please let us know.